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Remchugov, who has worked at the Institute of Immunization of the "Biologics" Research and Production Consortium for more than 20 years, said that the inactivated vaccine against tularemia they developed contains multiple components and is an all-round vaccine that can be regarded as a vaccine with a changeable "tip."
Usually, when humans encounter an unknown infectious disease, it takes a long time to confirm it. As an all-round vaccine, the inactivated anti-tularemia vaccine can quickly put the body's immune system into a "combat" state within a few hours. The "tip" of the vaccine "entangles" the pathogen and prevents the pathogen from being propagated on a large scale. This buys researchers a lot of time to study the characteristics of pathogens.
The development of inactivated vaccines is a new direction in the field of microbiology in recent years. Attenuated active vaccines are developed based on viruses and bacteria. The use of attenuated active vaccines not only prevents diseases, but also poses the risk of causing illnesses in humans. Because the injected vaccine will remain in the human body for several years or even ten years. These vaccines may also change over time and the external environment, which in turn has adverse effects on the human body. Especially for those very dangerous infectious diseases, such as plague, tularemia, etc., the use of attenuated live vaccines must be very cautious. On the contrary, inactivated vaccines will be eliminated from the body within a few weeks after promoting the body's immunity and will not cause harm to the human body. Therefore, it is most convenient for staff in dangerous and special occupations to use it.
Tularemia is a highly infectious disease that affects people and animals. Although rarely fatal and treatable with antibiotics, the disease can cause severe, long-term pneumonia-like symptoms and various gland and gastrointestinal disorders, making it extremely harmful to animals and humans.
Countries around the world have been developing vaccines to fight it for more than 60 years, but so far only Russian scientists have achieved success. It is reported that this scientific research result has been patented. (Editor in charge: Ye Huiling)