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There are more than a hundred kinds of non-steroidal anti-inflammatory drugs. What we commonly use now are aspirin, Emeline, Norzon, Lexone, Mobico, indometacin indomethacin, cinorol, ibuprofen, Fenbid, diclofenac sodium votaren, ketoprofen, naproxen, napperone, piroxicam, Yantongxikang, etc. These drugs have analgesic effects on patients with rheumatoid arthritis. However, many patients complain that all painkillers have been used, but they cannot solve the problem. What is the reason? There are some issues about medication principles and medication methods that patients may not understand very well.

Although non-steroidal anti-inflammatory drugs are all used for pain relief and anti-inflammation, the time when each drug exerts its best effect after being taken is different, and the side effects are also different. Not only that, the effects and side effects of these drugs on white people and yellow people are not exactly the same. For example, aspirin is cheap and has few side effects. It was used more in some countries in the past. However, patients in our country have poor tolerance to this drug and it is difficult to take it for a long time. We often encounter it in our work that Zhang uses indomethacin to have a good effect on indomethacin, while Li "prefers" ibuprofen. And so on, this is the so-called racial and individual differences.

After understanding this truth, we must pay attention to the individualization of medication. Patients should cooperate with their doctors to choose the non-steroidal anti-inflammatory drug that is most suitable for them. This choice inevitably requires a trial process, because doctors cannot make estimates for each patient in advance. Only through the trial process can we find reasonable medication methods, including the choice of the preferred drug, the dose of medication, the duration of medication, the maintenance amount of medication, etc. In general, most non-steroidal anti-inflammatory drugs take effect within a few days. Therefore, the time to observe the efficacy should not be too long. Usually, one drug is used alone for about two weeks. If the effect is not significant, another drug should be switched to. As mentioned earlier, the effectiveness of treatment depends on the role of each drug itself and individual differences. Therefore, every rheumatoid arthritis patient has to go through the trial phase of non-steroidal anti-inflammatory drugs.

It is generally not recommended to use two or more non-steroidal anti-inflammatory drugs at the same time in combination, because the use of one non-steroidal anti-inflammatory drug to a patient, as long as the dose is reasonable, has better effect than the combination of several small doses of non-steroidal anti-inflammatory drugs. Moreover, there are compatibility issues in combination, that is, only reasonable combination can enhance the efficacy. Otherwise, it will be counterproductive, with poor curative effect and large side effects.

If combined medication is needed, it is also necessary to distinguish the situation and control it flexibly. For example, some patients have particularly stiff joints when they get up in the morning, they can add a drug with a longer analgesic effect before going to bed the night before, such as UTO, Indomethacin Suppository, etc.

In addition, all non-steroidal anti-inflammatory drugs are harmful to the gastric mucosa. In order to improve the gastrointestinal tolerance during treatment with non-steroidal anti-inflammatory drugs, oral drugs should be taken simultaneously with food or immediately after meals; Drinking water at the same time; taking it straight; reducing factors that induce gastritis, such as smoking, drinking alcohol, etc.