What if the FTO gene causes people to be obese?

As people's living standards improve, there are more and more obese people, and obesity has become a serious health problem. Among the fat people, there are some people who seem to be born to be fat. Although they are unwilling and try to lose weight, they cannot escape the disaster of obesity. This is mainly due to the obesity gene.

The 'FTO' obesity gene doomed some people to be obese

The FTO gene is an allele associated with obesity, also known as the obesity gene. This gene was first identified in 2007 by researchers such as Mark McCarthy at the University of Oxford in the United Kingdom. It is located on chromosome 16 and has a double rotation structure, with two copies coming from the father and mother respectively. FTO has been called the most common gene associated with obesity by scientists. German and American experts have found through research that the impact of the FTO gene on human obesity is mainly due to its influence on the expression of IRX3 and IRX5 genes. The FTO gene can remotely activate the expression of IRX3 and IRX5 genes in a certain variant region, causing prefat cells to differentiate into fat cells and lose the ability to burn fat to produce calories, thereby causing the body to be unbalanced and causing the body to be overweight.

People carrying the FTO gene have a strong desire to eat. Normal "three meals a day" cannot eliminate the hunger of FTO gene carriers, causing them to keep eating. Because of the lack of control over their diet, high-calorie and high-fat foods are extremely tempting to them. When they are hungry, they tend to eat this type of food. In addition, FTO also suppresses people's metabolism, making it difficult for body fat to be burned to produce calories, and excess fat accumulates in the body, making people obese.

The impact of the FTO gene on human obesity is the research direction of many scientists. At present, scientists have a rough understanding of the mechanism of the FTO gene's action, but they have not yet been able to invent a drug based on this to control obesity caused by the effect of the FTO gene.

How to lose weight when you are born obese?

There is no drug that can treat obesity caused by the effect of FTO. If you get the "curse" of the FTO gene, will you not be able to lose weight? Of course not. The obesity gene is hereditary. You can't get the obesity gene out of you, but you can change the strength of the obesity gene through positive methods.

1. Keep exercising every day

Swedish experts have found through experiments that some genes that regulate obesity metabolism lose methyl groups after strenuous exercise, allowing fat to be easily converted into protein, achieving weight loss. In other words, people can use exercise to weaken the ability of the obesity gene. People who are born obese need to maintain a certain amount of exercise every day. It is recommended to insist on aerobic exercise for more than one hour a day, while strength training is done for more than 20 minutes a day and 2 to 3 times a week.

2. Eat according to your genetic type

Between heaven and earth, one thing descends another, and so does the obesity gene. The obesity gene can make people fat, but on the other hand, there are natural substances that can inhibit its effect. Studies have found that the impact of high-protein foods on weight loss is related to the rs155890 locus on the FTO gene. People carrying the mutant gene at this locus eat a certain amount of high-protein foods, which has a better effect on weight loss; fermented soy products have a better effect on weight loss. The impact of fermented soy products on weight loss is related to the rs9282541 locus on the ABCA1 gene. People carrying the mutant gene at this locus eat a certain amount of fermented soy products, which can help burn fat and achieve the goal of weight loss.

3. release pressure

British researchers have been studying the workplace for 19 years and found that the incidence of obesity among people with high work stress is 73% higher than that of people with low stress." This study shows that stress activates the obesity gene and makes people fat. Therefore, if you want to change the obesity gene, you need to release stress. There are many ways to relieve stress, including exercise, travel, watching movies, shopping, etc., but never use the idea of "eating" to solve your stress, otherwise it will only make you fatter and fatter.

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