Research finds that eating peppers can suppress appetite and lose weight

Researchers at the University of Adelaide have found that a high-fat diet may weaken an important receptor in the stomach that produces a feeling of fullness.

An article published in the journal PLOS ONE shows that researchers at the Center for Nutrition and Gastrointestinal Diseases of the South Australia Institute of Health and Medical Research are studying the relationship between the hot pepper receptor TRPV1 in the stomach and the feeling of satiety in the laboratory.

"When the stomach is filled with food, the stomach begins to elongate. Food stimulates nerves in the stomach to tell the body that the stomach is full. We found that this activation process is regulated by pepper or hot pepper receptors." said Amanda Page, senior researcher associate professor.

Previous studies have found that capsaicin in hot peppers reduces food intake. The reduction in hot pepper receptors we found suppresses the response of the gastric tension nerve, leading to a delay in feeling full and consuming more food. Therefore, part of the effect of capsaicin on food intake may be mediated through the stomach.

"We also found that hot pepper receptors block the high-fat diet that causes obesity." Amanda Page said. Dr. Stephen Kentish said the findings will lead to further research and the development of new treatments.

"It's exciting that we now know more about the hot pepper receptor pathway and that consuming capsaicin can prevent overeating by stimulating nerves in the stomach," Dr. Kentish said.

"The next phase of research will include investigating the mechanisms of hot pepper receptor activation, with the goal of developing better treatments.

"We will also do further work to determine why a high-fat diet reduces the sensitivity of hot pepper receptors and study whether we can reverse such damage."

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